Complement system - Wikipedia
The complement system, also known as complement cascade, is a part of the humoral, innate immune system and enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promote inflammation, and attack the pathogen's cell membrane. [1]
Complement System Function - Cleveland Clinic
The complement system is part of your body’s immune system that cleans up damaged cells, helps your body heal after an injury or an infection and destroys microscopic organisms like bacteria that make you sick.
The complement system and innate immunity
Complement is a system of plasma proteins that can be activated directly by pathogens or indirectly by pathogen-bound antibody, leading to a cascade of reactions that occurs on the surface of pathogens and generates active components with various effector functions.
Complement | Description, Function, & Activation | Britannica
2024年10月7日 · Complement, in immunology, a complex system comprising a large number of proteins that act in concert to help eliminate infectious microorganisms. Specifically, the complement system causes the lysis (bursting) of foreign and infected cells, the phagocytosis (ingestion) of foreign particles and.
Complement System | British Society for Immunology
The complement system plays a critical role in inflammation and defence against some bacterial infections. Complement may also be activated during reactions against incompatible blood transfusions, and during the damaging immune responses that accompany autoimmune disease.
The complement system: history, pathways, cascade and inhibitors
2012年2月2日 · The complement system is an integral part of the innate immune response and acts as a bridge between innate and acquired immunity. It consists of a series of proteins that are mostly (although not exclusively) synthesised in the liver, and exist in the plasma and on cell surfaces as inactive precursors (zymogens).
Complement and its role in innate and adaptive immune responses
2009年12月15日 · The complement system comprises a far-reaching and vital component of innate immunity and represents one of the major effector mechanisms of the innate immune system.
A guide to complement biology, pathology and therapeutic
2023年9月5日 · Complement has long been considered a key innate immune effector system that mediates host defence and tissue homeostasis. Yet, growing evidence has illuminated a broader involvement of...
Complement System - Complement System - Merck Manual Professional Edition
The complement system is an enzyme cascade that helps defend against infection via activation of a local inflammatory response. Many complement proteins occur in serum as inactive enzyme precursors (zymogens); others reside on cell surfaces.
Complement: a key system for immune surveillance and …
2010年8月19日 · Complement acts as a rapid and efficient immune surveillance system that has distinct effects on healthy and altered host cells and foreign intruders.