Anti-CD3 Antibodies | Invitrogen - Thermo Fisher Scientific
Find the CD3 antibody that fits your needs. Choose from 1 of 500 CD3 antibodies, which have been validated in experiments with 9796 publications and 3872 images featured in our data gallery. Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications.
Therapeutic anti-CD3 monoclonal antibodies: from bench to …
Investigations over the last 20 years have shown that anti-CD3 monoclonal antibodies (mAbs) effectively treat autoimmune disease in animal models and have also shown promise in clinical trials. Tolerance induction by anti-CD3 mAbs is related to the induction of Tregs that control pathogenic autoimmune responses.
CD3-specific antibodies: a portal to the treatment of …
2007年7月20日 · This Review summarizes the pre-clinical and clinical studies of CD3-specific monoclonal antibody therapy and highlights future opportunities to enhance the efficacy of this potent...
Anti-CD3: the agonist and the ecstasy - Nature
2021年6月17日 · Orthoclone OKT3 targets the CD3 molecule that is present exclusively on T cells and depletes them from the circulation, which makes the drug an effective immunomodulator.
Mini-review: The T Cell Marker, CD3 Antigen and Antibodies
CD3 is an essential T cell co-receptorand defines T cell lineage. CD3is therefore an ideal T cell marker. This mini-review explains the structure of CD3, the genes involved in its expression, its function and the signal transduction pathways mediated by CD3 complex.
CD3-specific antibody-induced active tolerance: from bench to …
2003年2月1日 · Monoclonal CD3-specific antibodies that recognize the ε-chain of the CD3 complex are potent immunosuppressants. They were introduced in clinical transplantation in the early 1980s to prevent...
Anti-CD3 antibody [CD3-12] (ab11089) - Abcam
Anti-CD3 antibody [CD3-12] Rat Monoclonal CD3E antibody. Suitable for IHC-P, WB, Flow Cyt (Intra) and reacts with Mouse, Rat, Human samples. Cited in 104 publications. Immunogen corresponding to Synthetic Peptide within Human CD3 epsilon. 18 reviews.
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Purified anti-human CD3 Antibody anti-CD3 - OKT3 - BioLegend
The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex. Clone OKT3 can block the binding of clones SK7 and UCHT1. 4 The OKT3 antibody is able to induce T cell activation.
CD3 Antibody - an overview | ScienceDirect Topics
Anti-CD3 antibodies. Anti-CD3 antibodies act as potent immunosuppressive agents by modulating the CD3/T-cell receptor (TCR) complex. They have been used in patients to prevent short term allograft rejection and were also shown to induce long-term remission of autoimmune diabetes in nonobese diabetic (NOD) mice [8].
CD3 Antibodies - Novus Biologicals
Browse our extensive catalog for monoclonal antibodies and CD3-conjugated antibodies. Validated research applications for CD3 antibodies include CyTOF-ready, Flow Cytometry, ICC, Immunofluorescence, Knockdown-validated IHC, IHC-Frozen, IHC-Paraffin, IP, and Western Blot.
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