BACKGROUND: Evaluation of whether dyspnea has a cardiac cause is essential. Guidelines from 2016 were reported to result in a high incidence of indeterminate left ventricular (LV) filling pressure. We ...

Research studies in cardiovascular epidemiology assessing the relationship between a primary exposure and a health outcome must account for the presence of what are often called third variables, ...

BACKGROUND: Penetrance and risk of ventricular arrhythmias (VAs) in arrhythmogenic right ventricular cardiomyopathy (ARVC) are increasingly recognized as being genotype specific. Therefore, ...

The protein risk score formula developed from the UKB-PPP derivation set was composed of 165 unique plasma proteins, and 15 of them were associated with atrial remodeling. In the UKB-PPP test set, a 1 ...

The 2023 Predicting Risk of Cardiovascular Disease Events (PREVENT) equations estimate the risk of incident cardiovascular disease (CVD). Developed and validated in 25 data sets with >6 million ...

Ultrasound‐enhancing agents (UEAs) improve diagnostic transthoracic echocardiography (TTE) in selected cardiac patients. UEA use has been embraced by the cardiology community, and there is now an ...

BACKGROUND: Carotid web is a rare and likely underrecognized cause of ischemic stroke, particularly in young patients. Given the high risk of recurrence, diagnostic delays may have serious ...

BACKGROUND: Long-term outcomes and quality of life have been identified as core patient-centered outcomes for venoarterial extracorporeal membrane oxygenation (VA-ECMO) research. The aim of this study ...

BACKGROUND: Tissue-level hypoperfusion (no-reflow) persists in 30% of patients with seemingly successful upstream angiographic recanalization at thrombectomy. We investigated the clinical impact of ...

The effect of these interrelated, sometimes competing and sometimes complementary, trends on clinical practice in the United States has not been clearly defined. In this issue of the Journal, Stehlik ...

BACKGROUND: Symptomatic severe aortic stenosis (AS) remains undertreated with high resultant mortality despite increased growth and availability of aortic valve replacement (AVR) since the advent of ...

Among 1190 ICH patients analyzed, the mean age was 61 years old, and 62% of the cohort were males. Lower baseline hemoglobin levels are associated with increased odds of hematoma expansion (adjusted ...