Background Early-life inflammation has long been recognised as a key pathophysiological process in the evolution of cystic ...

Background Vitamin A, an essential micronutrient obtained through the diet, plays a crucial role in lung development and contributes to lung regeneration. We aimed to investigate its effect on adult ...

Background Severe obesity causes respiratory morbidity and mortality. The impact of obesity on the mechanics of breathing is not fully understood. Conclusions Obese subjects have markedly increased ...

Rationale Pulmonary rehabilitation is an effective treatment for people with chronic respiratory disease but is delivered to <5% of eligible individuals. This study investigated whether home-based ...

7 Public Health Department of Gipuzkoa, San Sebastian, Gipuzkoa, Spain Background Effects of prenatal and postnatal exposure to air pollution on lung function at preschool age remain unexplored. We ...

Correspondence to Dr Harm Tiddens, Department of Paediatric Pulmonology and Allergology, Erasmus MC Sophia Children Hospital, Rotterdam, 3015 CN, The Netherlands; h.tiddens{at}erasmusmc.nl Background ...

Correspondence to Dr Jamilah Meghji, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK; jamilah.meghji{at}lstmed.ac.uk Background Post-tuberculosis lung ...

5 Department of Medicine, Faculty of Medicine, University of Valencia, Valencia, Spain 6 Department of Pharmacology, Faculty of Medicine, University of Valencia, Valencia, Spain Correspondence to Dr ...

BACKGROUND The guidelines on chemotherapy and management of tuberculosis in the United Kingdom have been reviewed and updated. METHODS A subcommittee was appointed by the Joint Tuberculosis Committee ...

Background Previous studies have reported an association between weight increase and excess lung function decline in young adults followed for short periods. We aimed to estimate lung function ...

Background: Rhinovirus infection is responsible for considerable morbidity and mortality as the major cause of exacerbations of asthma, and is also known to induce exacerbations of cystic fibrosis and ...

3 The University of Manchester, Manchester Academic Health Science Centre, University Hospital South Manchester NHS Foundation Trust, Manchester, UK 4 University Hospital of South Manchester, ...