Introduction and Objectives The interaction between hospitalisation for acute lower respiratory tract infection (LRTI), COPD status, and subsequent ACS is infrequently reported. Proposed mechanisms ...

Objectives Infliximab, an anti-TNF agent, is used to treat sarcoidosis that does not respond to corticosteroids or second-line agents. The efficacy of other anti-TNF agents, non-TNF biologics and ...

Both common and rare variants contribute to the genetic architecture of pulmonary fibrosis. Genome-wide association studies have identified common variants, or those with a minor allele frequency of ...

Background Debate about the optimal lung cancer screening strategy is ongoing. In this study, previous screening history of the Dutch-Belgian Lung Cancer Screening trial (NELSON) is investigated on if ...

Background: Chronic obstructive pulmonary disease (COPD) is characterised by both an accelerated decline in lung function and periods of acute deterioration in symptoms termed exacerbations. The aim ...

Abstract These guidelines have been replaced by 2010 Guideline On Radical Management Of Patients With Lung Cancer and NICE Lung Cancer Guideline CG121 2011 Superseded By 2010 Guideline On Radical ...

BACKGROUND Historical cohort studies in England have found that impaired fetal growth and lower respiratory tract infections in early childhood are associated with lower levels of lung function in ...

Pleural haematoma secondary to spontaneous rupture of an intercostal artery aneurysm is extremely rare but can be life-threatening. Most documented cases have been associated with coarctation of the ...

Background The lower airway microbiota in patients with chronic obstructive pulmonary disease (COPD) are likely altered compared with the microbiota in healthy individuals. Information on how the ...

This guideline is based on a comprehensive review of the literature on pulmonary nodules and expert opinion. Although the management pathway for the majority of nodules detected is straightforward it ...

SUMMARY OF KEY RECOMMENDATIONS FOR EMERGENCY OXYGEN USE Achieving desirable oxygen saturation ranges in acute illness (sections 6.7 and 6.8) This guideline recommends aiming to achieve a normal or ...

Background Idiopathic pulmonary fibrosis (IPF) is characterised by damage to the epithelial layer, closely associated with the alveolar basement membrane (BM). We aimed to investigate how type IV ...