Aims To explore the experiences and perceptions of senior medical and nursing staff regarding the advance care plan (ACP) in children and young persons (CYP) with life-limiting conditions and ...

Aims Maternal breastmilk (MBM) is the one of the most important interventions a preterm infant can receive. It reduces morbidity, improves neurodevelopmental outcome and reduces the incidence of ...

Aims The HEADSSS assessment is an internationally used tool to help give structure and framework to an assessment of an adolescent patient. Objective To analyze the knowledge among doctors in the ...

Methods We used novel linkage between health and education records from the Education and Child Health Insights from Linked Data (ECHILD) database to develop a whole-country cohort of children ...

Objectives Asthma is the most common chronic condition in children, affecting 2–3 in every primary school class.1 Asthma disproportionately affects children living in poverty due to air pollution, ...

Introduction More than half of all drugs are still prescribed off-label to children. To support off-label dosing, pharmacokinetic (PK) data are needed. Physiologically-based pharmacokinetic (PBPK) ...

BACKGROUND In recent years photopheresis, an extracorporeal form of photochemotherapy using psoralen and ultraviolet A irradiation of leucocytes, has been claimed to be an effective form of ...

On 20 February 2020, so-called Italian Patient 1 was admitted to the intensive care unit of his local hospital due to a deteriorating clinical condition from SARS-CoV-2/COVID-19 infection. In Italy, ...

Introduction Bronchiolitis is a very common acute respiratory illness affecting infants and is a significant cause of acute morbidity in the first 12 months of life. The diagnosis of bronchiolitis is ...

For anyone, undergoing surgery is stressful. For children on the autism spectrum, it can be even more traumatic. Sensory differences are present in the majority of children on the autism spectrum,1 ...

Rational prescribing of medicines requires evidence from clinical trials on efficacy, safety and the dose to be prescribed, based on clinical trials. Regulatory authorities assess these data and ...

We encounter, occasionally, parents who are incapable of making medical decisions on behalf of their incompetent or ...