Parasitic tapeworm larvae release glutamate and other excitatory molecules that can directly excite brain neurons.

Neurotransmitters are the words our brain cells use to communicate with one another. For years, researchers relied on tools that provided limited temporal and spatial resolution to track changes in ...

When glutamate is too high and GABA levels are too low, as is the case with fibromyalgia and ME/CFS, symptoms like hyperalgesia (heightened sensitivity to pain), anxiety, restlessness, brain fog ...

Glutamate fuels brain tumor growth Glutamate is one of the principal neurotransmitters in the brain, but in excess can be highly neurotoxic. In September Nature Medicine Takahiro Takano and colleagues ...

Discover how the brain's most abundant neurotransmitter, glutamate, is revolutionizing psychiatry and offering new hope for depression, bipolar disorder, and more.

Glutamate's Role in Brain Communication Unveiled by High-Tech Imaging A study led by Johns Hopkins scientists captures how glutamate opens AMPA receptors, a step crucial for neuron signaling.

Johns Hopkins researchers used cryo-electron microscopy to study how glutamate opens AMPA receptors, which control brain signaling. The findings could help develop new drugs for conditions like ...

Scientists have mapped the molecular structure of glutamate receptors in the cerebellum for the first time using cryo-electron microscopy.

Chronic pain affects millions of people in the US. Targeting an oft-overlooked brain receptor could one day offer relief.