We have investigated the role of mitochondrial calcium buffering in excitotoxic cell death. Glutamate acts at NMDA receptors in cultured rat forebrain neurons to increase the intracellular free ...

Magnesium threonate supports brain health, enhances memory, reduces migraines, and may help prevent cognitive decline.

Monitored for 10 days leading up to the ketamine experiment, Johnson's brain activity followed fixed, predictable patterns.

Increasing gamma-aminobutyric acid (GABA) and balancing glutamate, brain chemicals called neurotransmitters, may help alleviate symptoms of fibromyalgia (FMS) and chronic fatigue syndrome (ME/CFS).

A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with ...

The fatigue that comes from performing demanding mental tasks may stem from a buildup of the neurotransmitter glutamate, according to research published today (August 11) in Current Biology. Mental ...

Now, new research from the Warren Center for Neuroscience Drug Discovery (WCNDD) offers hope. Scientists have identified a ...

Some nerve cells in the brain involved in mood use a chemical called glutamate to communicate with each other. The nerve cells need glutamate receptors – think of them like catcher’s mitts for ...

Irritable bowel syndrome (IBS) is a common digestive disorder with unclear causes, affecting about 10% of the global population. Researchers from Japan have now discovered that opioid delta-receptor ...

Neurotransmitters are the words our brain cells use to communicate with one another. For years, researchers relied on tools that provided limited temporal and spatial resolution to track changes in ...

The findings point the way to treatment options targeting group 1 metabotropic glutamate receptors. This study is a major step toward the ultimate goal of treating fragile X syndrome (FXS), an ...