The multiple challenges of managing large-scale PV wastes demand a proactive approach; the costs of being underprepared or unprepared far outweigh those of early preparation. We must anticipate the ...

A cure for chronic hepatitis B requires eliminating or permanently silencing covalently closed circular DNA (cccDNA). A pivotal target of this approach is the hepatitis B virus (HBV) X protein (HBx), ...

The Cry proteins are pore-forming toxins produced by various strains of Bt to aid the bacteria in killing and growing on insects that happen to consume bacterial spores loaded with these crystalline ...

To better understand the potential health threats and underlying visual pathways of long-term light at night (LAN) exposure, we adopted a widely accepted diurnal animal model tree shrew (Tupaia ...

Natural ice plays salient roles in making the Earth habitable and sustainable. Previously overlooked, its role in chemical processes is now of emerging interest, particularly due to the freeze ...

Developing oral biologics has long been a holy grail of protein engineering. Traditional antibodies are large and unstable in the presence of gastrointestinal proteases. Here, we present a strategy to ...

Greening immediately after etiolated-seedling’s emergence from the soil is critical for plants to initiate their autotrophic life cycle through photosynthesis. The greening process relies on a complex ...

The proteasome is a protein complex that degrades proteins by cleaving substrates into smaller peptides. Most unwanted cellular proteins are earmarked for proteasome-mediated degradation by multimers ...

This study was supported by NSF Grants (Award Nos. 1354479, 1755130, and 2310983), Templeton World Charity Foundation (Grant No. 30059), US Federal Hatch project funds, and an International Union for ...

Efforts to anticipate and adapt to future climate can benefit from historical experiences. We examine agroclimatic conditions over the past 50 y for five major crops around the world. Most regions ...

The study of the role of disease mutation and selecting tauopathy-specific pathways was supported by the NIH under Grant Number R01AG05605. The study of the minimal prion design and seeding of tau was ...

Regional high-resolution climate projections are crucial for many applications, such as agriculture, hydrology, and natural hazard risk assessment. Dynamical downscaling, the state-of-the-art method ...