Objectives Asthma is the most common chronic condition in children, affecting 2–3 in every primary school class.1 Asthma disproportionately affects children living in poverty due to air pollution, ...

Introduction More than half of all drugs are still prescribed off-label to children. To support off-label dosing, pharmacokinetic (PK) data are needed. Physiologically-based pharmacokinetic (PBPK) ...

Objectives Hand dominance usually develops in children around 18 months old, while earlier hand preference may indicate cerebral palsy.1 Hand preference in humans is thought to be related to the ...

Methods We used novel linkage between health and education records from the Education and Child Health Insights from Linked Data (ECHILD) database to develop a whole-country cohort of children ...

Aims The HEADSSS assessment is an internationally used tool to help give structure and framework to an assessment of an adolescent patient. Objective To analyze the knowledge among doctors in the ...

For anyone, undergoing surgery is stressful. For children on the autism spectrum, it can be even more traumatic. Sensory differences are present in the majority of children on the autism spectrum,1 ...

Many additives, some of which have no nutritional value, can be legally used in processed foods. They intensify colour, thicken, increase shelf life and enhance flavour. Regulatory authorities issue ...

Methods Our aim in this observational study was to assess safety of the delivery room cuddles for babies born < 32 weeks’ gestation. As part of the stabilisation for babies born < 32 weeks, if certain ...

The hierarchy of evidence in assessing the effectiveness of interventions or treatments is explained, and the gold standard for evaluating the effectiveness of interventions, the randomised controlled ...

Objectives Describe clinical characteristics, treatment and outcomes of children treated for life-threatening pertussis in paediatric intensive care units during the 2023–2024 outbreak in Great ...

Objective Complete congenital heart block (CHB) due to anti-Ro/La antibodies in pregnancy can lead to adverse fetal outcomes and neonatal death. National and international guidelines do not recommend ...

Objectives To describe the incidence of new onset paediatric diabetes mellitus, clinical characteristics and patterns of presentation to emergency departments (ED) during the COVID-19 pandemic, and to ...