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5Department of Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. 6Department of Pharmaco-Therapy, -Epidemiology and- Economy, ...

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1Edwin L. Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. 2Department of Surgery, Keio ...

8Section of Hematology, Department of Internal Medicine, Yale University School of Medicine and Yale Cancer Center, New Haven, Connecticut.

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H. Ma and S. Srivastava are joint first authors of this article. R. Sundar and P. Tan are joint corresponding and senior authors of this article.

29Developmental Biology and Cancer Department, UCL GOS Institute of Child Health, London, United Kingdom. 32Haematology and Oncology Department, Great Ormond Street Hospital, London, United Kingdom.

1Wellcome Sanger Institute, Hinxton, United Kingdom. 2Department of Paediatrics, University of Cambridge, Cambridge, United Kingdom.