Drug resistance to doxorubicin is mediated through the ABCG2 protein by the TMEM158 gene.ABCG2 protein ( ATP-binding cassette sub-family G member. Is an efflux pump protein that actively transports ...

Research shows mitochondria form distinct subpopulations under nutrient stress, revealing survival mechanisms in cancer cells ...

An international team led by Goethe University Frankfurt has identified an intracellular sensor that monitors the quality of so-called MHC-I molecules, which help the immune system recognize and kill ...

Programmed cell death-1, or PD-1, has become a headline-grabbing molecule best known for its role in cancer immunotherapies ...

It is comparatively easy to tell a cell's state of health: On their surface, cells present fragments of almost all the proteins they contain inside. This means the immune system can directly recognize ...

In a groundbreaking discovery, scientists from Rice University and their collaborators have unveiled a remarkable approach to ...

This development may be a bit more surprising, though: According to an October 2024 study in the International Journal of ...

P5CS-containing mitochondria showed higher membrane potential ... specialized groups of mitochondria within a cell, including pancreatic cancer cells, such that each group focuses on different ...

To improve long-term persistence and reduce the risk of immune rejection, researchers are exploring ways to diminish the ...

Research indicates that cannabis use causes cellular damage that increases the risk of highly cancerous tumors by disrupting ...

Tumors find different ways to avoid immune cell detection and proliferate in their environment. Antitumor immune cells will ...

Many of us remember from high school biology class that mitochondria are the cell's "power plants." These small ...