Sex differences in heart cells may influence disease outcomes
Heart disease is the number one killer of men and women, but it often presents differently depending on sex. There are sex ...
High-speed microscopy reveals real-time protein translocation across a bacterial membrane
Protein translocation is an essential, nano-scale dynamic process that facilitates the movement of proteins across cellular ...
The EMBO Journal8 小时
Refuse in order to resist: metabolic bottlenecks reduce antibiotic susceptibility
Most mutations that decreased antibiotic susceptibility were related to specific metabolic pathways. A MIC-increase to ...
Patented Transdermal Drug Candidate From Vascarta May Offer A Convenient & Cost-Effective ...
Based in part on these favorable pre-clinical results, a clinical trial using VAS-101 in individuals with sickle cell disease will soon be initiated ...
生物通2 小时
PAP 和 DXO1 竟这样调控拟南芥 mRNA 降解，改写植物分子调控认知
为探究拟南芥中 CTRD 途径的调控机制，法国研究人员开展 PAP 和 DXO1 对其调控作用的研究。结果发现二者参与 CTRD 调控，意义重大。这一成果有助于深入理解植物 mRNA 调控，强烈推荐科研读者阅读。
腾讯网10 小时
Cell | COOL1 基因的自然突变增强了玉米的耐寒性，以适应高纬度地区 ...
原文：A natural variant of COOL1 gene enhances cold tolerance for high-latitude adaptation in maize关键词：COOL1，HY5，磷酸化，GWAS，自然变异，耐寒性，高纬度适应摘要：低温严重限制了玉米的生长、产量和地理分布️。玉米如何适应寒冷气候仍不清楚。本研究通过全基因组关联分析（GWAS）鉴定出 bHLH ...