The domestication of pigs (Sus scrofa) has had profound socioeconomic and ecological consequences. Although pigs are believed to have been independently domesticated in South China, the timing and ...

Main text Please take note of the following when preparing your manuscript for PNAS: Do not include statements of novelty or priority. Avoid laboratory jargon. Use correct chemical names. Specify ...

A cure for chronic hepatitis B requires eliminating or permanently silencing covalently closed circular DNA (cccDNA). A pivotal target of this approach is the hepatitis B virus (HBV) X protein (HBx), ...

We thank Jun Chen for providing wdr5 mutant, Anming Meng for providing rnaseh1 MO, Dengli Hong for providing 2×HBD, and Yu Sun for assistance during the experimental process. This work was supported ...

Resolving the complex evolutionary history of polyploid species like octoploid strawberry is challenging due to the number of potential progenitors and the potential for hybridization events within ...

Organic semiconductors (OSCs) are pivotal for next-generation flexible electronics but are limited by an intrinsic trade-off between mobility and stability. We introduce adaptive surface doping (ASD), ...

Many cities seek to alleviate extreme heat via planting trees. However, the cooling achieved by such programs is debated because previous analyses address scales much smaller than the whole-city scale ...

The discovery of Lophiostroma leizunia Jeon sp. nov., a 480-My-old phosphatic stromatoporoid sponge from South China, revolutionizes our understanding of early reef ecosystems and biomineralization.

Ryk Expression Is Induced in Injured Spinal Cords in Mice and Humans. The expression of a Wnt receptor, Ryk, known to mediate axon repulsion in development as well as in injured adult spinal cord, was ...

Regional high-resolution climate projections are crucial for many applications, such as agriculture, hydrology, and natural hazard risk assessment. Dynamical downscaling, the state-of-the-art method ...

A huge challenge for the application of few-layer two-dimensional (2D) materials in next-generation integrated circuits is synthesizing wafer-scale films with a strictly consistent number of layers ...

HIV-1 infection remains incurable because of the long-lasting HIV-1-infected latency cells residing in the host. Current treatment strategies are unable to completely eliminate the virus latent ...