Introduction We have developed a Simian Immunodeficiency Virus (SIV)-based lentiviral vector pseudotyped with the Sendai-virus envelope glycoproteins (F/HN) (rSIV.F/HN) that is effective at ...

Introduction and Objectives The interaction between hospitalisation for acute lower respiratory tract infection (LRTI), COPD status, and subsequent ACS is infrequently reported. Proposed mechanisms ...

Background Antimicrobial resistance (AMR) is a growing global health crisis and is particularly relevant to people living ...

Background There is emerging evidence suggesting a link between ambient heat exposure and chronic obstructive pulmonary disease (COPD) hospitalisations. Individual and contextual characteristics can ...

Rationale Dendritic cells (DC) accumulate in the lungs of patients with idiopathic lung fibrosis, but their pathogenetic relevance is poorly defined. Objectives To assess the role of the FMS-like ...

British Thoracic Society guideline for the use of long-term macrolides in adults with respiratory disease ...

Objectives Infliximab, an anti-TNF agent, is used to treat sarcoidosis that does not respond to corticosteroids or second-line agents. The efficacy of other anti-TNF agents, non-TNF biologics and ...

Background Evidence suggests that patients with COPD struggle to maintain improved physical activity (PA) after completing pulmonary rehabilitation (PR). Smartphone applications (apps) providing a ...

Rationale Advance care planning (ACP) is uncommon in patients with chronic obstructive pulmonary disease (COPD). Objectives To assess whether a nurse-led ACP-intervention can improve quality of ...

To examine the role of smoking on the bacterial community composition of the upper and the lower respiratory tract, a monocentric, controlled prospective study was performed, including healthy smokers ...

Target audience for the guideline The guideline will be of interest to UK based clinicians caring for adults with pleural disease, including chest physicians, respiratory trainees, specialist ...

The clinical presentation of Aspergillus lung disease is determined by the interaction between fungus and host. Invasive aspergillosis develops in severely immunocompromised patients, including those ...