Musunuru and colleagues 1 describe in the Journal an innovative approach in which gene editing is applied in the treatment of a very rare disease, the severe urea-cycle disorder carbamoyl ...

Semaglutide at a dose of 2.4 mg has established weight-loss and cardiovascular benefits, and cagrilintide at a dose of 2.4 mg ...

In previous treat-to-target trials, adjustments to the dose of basal insulin have been made at least weekly, according to ...

Corporatization” of health care, a process predicted decades ago, now refers to the general trend throughout the industry ...

A 63-year-old woman was evaluated for dyspnea and edema. Soft-tissue thickening was noted in the retroperitoneum and mediastinum and around the heart and vessels. A diagnosis was made.

The prevalence and incidence of atopic dermatitis have increased over the past several decades. 2,3 The Global Burden of Disease study showed a prevalence of 15 to 20% among children and up to 10% ...

Explore this issue of The New England Journal of Medicine (Vol. 0 No. 0).

Supported in part by the Norwegian Dementia Genetics Network (DemGen), a grant (REC2018/915) from the HUSK study, a grant (REC2016/1226) from the MoBa study, grants (344121 to Drs. Andreassen and ...

The United States has the world’s highest incarceration rate. 1 At the end of 2020, despite historic declines in the incarcerated population due to Covid-19, 1.7 million people in the United ...

One of the more difficult decisions for patients with poorly controlled type 2 diabetes, as well as for their clinicians, is ...

Most rotator-cuff tears are degenerative, atraumatic, and more prevalent with age. Nonoperative treatment, including physical therapy, is typically recommended; surgery is considered in some cases.

Chronic meningitis is broadly characterized as infectious or noninfectious (Table 1). Geographic region of residence, travel, immune status, and underlying illnesses are the initial building ...