The term idiopathic neutropenia describes a benign disorder of granulopoiesis characterized by the unexplained reduction in the absolute neutrophil ... pathogenetic mechanisms: first, the primary ...

Nearly 150 years ago, scientists discovered that specialized blood cells serve a vital role in immune system protection ...

Expert Rev Hematol. 2008;1(2):217-229. Another important issue is prevention of osteoporosis in CIN patients. Apart from the conventional bone-mineral density measurement, we recommend evaluation ...

However, the actual molecular mechanism of the anti-inflammatory ... Antithrombin stimulates CLEC1A on human neutrophil cells to change the morphology of neutrophils to a spherical shape with ...

Using blood progenitor cell lines that can be induced to undergo maturation towards fully functional neutrophils, we are elucidating the molecular mechanisms that control neutrophil differentiation ...

Antithrombin strongly regulated human neutrophils by stimulating the identified ... However, the actual molecular mechanism of anti-inflammatory effect of antithrombin was completely unknown.

SAN DIEGO--(BUSINESS WIRE)--Onchilles Pharma, a private biotech company developing pan-cancer therapeutics that leverage the ELANE pathway, a novel innate immune mechanism of action for potent and ...