We have investigated the role of mitochondrial calcium buffering in excitotoxic cell death. Glutamate acts at NMDA receptors in cultured rat forebrain neurons to increase the intracellular free ...

Cornell researchers have identified a specific brain circuit that could lead to anxiety treatments without cognitive side effects.

Increasing gamma-aminobutyric acid (GABA) and balancing glutamate, brain chemicals called neurotransmitters, may help alleviate symptoms of fibromyalgia (FMS) and chronic fatigue syndrome (ME/CFS).

Dissociation is the brain’s defense against overwhelming stress, involving altered brain regions, neurotransmitters, and hormones. Dissociation can impair emotions and memories.

Sleep's role to down-scale glutamate, excitatory, frontal cortical synapses is extended to include an up-scaling of metaplastic LTP potential, in recovery from prolonged waking induced saturation of ...

Scientists have pinpointed a brain circuit that, when activated, reduces anxiety without impairing memory. Using ...