They found that densely packed chromosomal material, called heterochromatin, was not only localized to the inside ofthe nuclear membrane, as is the case in beta-actin-containing cells, but was ...

Transcriptome-wide measurement of subcellular mRNA dynamics in mouse ES cells reveals that nuclear retention is the ...

Science Piercing the nucleus of a cell without destroying it seems like a technical feat. Yet, researchers have just found a non-invasive method that could revolutionize gene therapies. A series of ...

Jahed added, “It is not easy to get anything into the nucleus. Drug and gene delivery through the nuclear membrane has long been an immense challenge.” Current methods to access the nucleus typically ...

Nat Genet. 2020 Sep;52(9):884-890. doi: 10.1038/s41588-020-0667-5. Epub 2020 Jul 27. PMCID: PMC7484228. Maciejowski J, Hatch EM. Nuclear Membrane Rupture and Its Consequences. Annu Rev Cell Dev Biol.

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science ...

These membranes, composed of flexible lipid bilayers, can reshape and remodel themselves during processes like cell movement, division, and molecular trafficking. Until now, it was commonly assumed ...

A team led by Prof. Wang Chao and Prof. Huang Chengdong from the University of Science and Technology of China (USTC) of the ...