An international team led by Goethe University Frankfurt has identified an intracellular sensor that monitors the quality of so-called MHC-I molecules, which help the immune system recognize and kill ...

It is comparatively easy to tell a cell's state of health: On their surface, cells present fragments of almost all the proteins they contain inside. This means the immune system can directly recognize ...

It is comparatively easy to tell a cell's state of health: On their surface, cells present fragments of almost all the proteins they contain inside. This means the immune system can directly recognize ...

Drug resistance to doxorubicin is mediated through the ABCG2 protein by the TMEM158 gene.ABCG2 protein ( ATP-binding cassette sub-family G member. Is an efflux pump protein that actively transports ...

One approach engages T cells to kill tumor cells by combining high-affinity binding to a tumor-associated antigen with low-affinity binding to CD3 on the T cell membrane. Another uses a target ...

When these membrane-coated nanoparticles are injected back into the patient, the cell membrane acts as a guide, directing the nanoparticles to the tumor cells with precision.

In many types of cancer, tumor cells have an overabundance of specific membrane proteins; this often grants them special properties, such as accelerated growth, immune system avoidance ...

When the gene that codes for EGFR has a mutation, it affects the way this protein works, causing cancer. There are many types of EGFR mutations. The EGFR protein lives in the cell membrane with ...

This study highlights the relationship between polyunsaturated fatty acids and cancer risk, suggesting blood biomarkers may be key for accurate assessment.